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Haplotype-based approach to known MS-associated regions increases the amount of explained risk

Genome-wide association studies (GWAS), using single nucleotide polymorphisms (SNPs), have yielded 110 non-human leucocyte antigen genomic regions that are associated with multiple sclerosis (MS). Despite this large number of associations, however, only 28% of MS-heritability can currently be explai...

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Foilsithe in:J Med Genet
Main Authors: Khankhanian, Pouya, Gourraud, Pierre-Antoine, Lizee, Antoine, Goodin, Douglas S
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552900/
https://ncbi.nlm.nih.gov/pubmed/26185143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103071
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