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Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways

Candida albicans is both a major fungal pathogen and a member of the commensal human microflora. The morphological switch from yeast to hyphal growth is associated with disease and many environmental factors are known to influence the yeast-to-hyphae switch. The Ras1-Cyr1-PKA pathway is a major regu...

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Pubblicato in:PLoS Pathog
Autori principali: Grahl, Nora, Demers, Elora G., Lindsay, Allia K., Harty, Colleen E., Willger, Sven D., Piispanen, Amy E., Hogan, Deborah A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552728/
https://ncbi.nlm.nih.gov/pubmed/26317337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005133
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