Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation

Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO), a phenazine secreted by Pseudomonas aeruginosa, inhibits both C. albicans biofilm formation and development of wrinkled colonies. Using a genetic screen, we identified two...

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Detalhes bibliográficos
Main Authors: Lindsay, Allia K., Morales, Diana K., Liu, Zhongle, Grahl, Nora, Zhang, Anda, Willger, Sven D., Myers, Lawrence C., Hogan, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183431/
https://ncbi.nlm.nih.gov/pubmed/25275466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004567
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