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Regulated proteolysis of Candida albicans Ras1 is involved in morphogenesis and quorum sensing regulation

In Candida albicans, a fungal pathogen, the small G-protein Ras1 regulates many important behaviors including white-opaque switching, biofilm formation, and the induction and maintenance of hyphal growth. Like other Ras proteins, Ras1 is activated upon guanine triphosphate binding, and its activity...

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Bibliographic Details
Main Authors: Piispanen, Amy, Grahl, Nora, Hollomon, Jeffrey M., Hogan, Deborah A.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782256/
https://ncbi.nlm.nih.gov/pubmed/23692372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12268
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