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Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis

Candida albicans hypha formation which has been stimulated via the Ras1-cAMP-Efg1 signalling cascade is inhibited by farnesol, a C. albicans autoregulatory factor, and small molecules such as dodecanol. In cultures containing farnesol or dodecanol, hypha formation was restored upon addition of dibut...

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Main Authors: Davis-Hanna, Amber, Piispanen, Amy E., Stateva, Lubomira I., Hogan, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782305/
https://ncbi.nlm.nih.gov/pubmed/18078440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.06013.x
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