The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.

Thrombocytopenia is a condition of multiple etiologies affecting the megakaryocyte lineage. To perturb this lineage in transgenic mice, the tsA58 mutation of the simian virus 40 large tumor antigen was targeted to megakaryocytes using the platelet factor 4 promoter. Ten of 17 transgenic lines genera...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Robinson, M O, Zhou, W, Hokom, M, Danilenko, D M, Hsu, R Y, Atherton, R E, Xu, W, Mu, S, Saris, C J, Swift, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12798
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!