The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice.

Thrombocytopenia is a condition of multiple etiologies affecting the megakaryocyte lineage. To perturb this lineage in transgenic mice, the tsA58 mutation of the simian virus 40 large tumor antigen was targeted to megakaryocytes using the platelet factor 4 promoter. Ten of 17 transgenic lines genera...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Robinson, M O, Zhou, W, Hokom, M, Danilenko, D M, Hsu, R Y, Atherton, R E, Xu, W, Mu, S, Saris, C J, Swift, S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC45527/
https://ncbi.nlm.nih.gov/pubmed/7809123
Tagiau: Ychwanegu Tag
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