Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

Chikungunya virus (CHIKV), the causative agent of a major epidemic spanning five continents, is a positive stranded mRNA virus that replicates using the cell’s cap-dependent translation machinery. Despite viral infection inhibiting mTOR, a metabolic sensor controls cap-dependent translation, viral p...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Joubert, Pierre-Emmanuel, Stapleford, Kenneth, Guivel-Benhassine, Florence, Vignuzzi, Marco, Schwartz, Olivier, Albert, Matthew L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552638/
https://ncbi.nlm.nih.gov/pubmed/26317997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005091
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker