Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data

Recently, several experimental techniques have emerged for probing RNA structures based on high-throughput sequencing. However, most secondary structure prediction tools that incorporate probing data are designed and optimized for particular types of experiments. For example, RNAstructure-Fold is op...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wu, Yang, Shi, Binbin, Ding, Xinqiang, Liu, Tong, Hu, Xihao, Yip, Kevin Y., Yang, Zheng Rong, Mathews, David H., Lu, Zhi John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551937/
https://ncbi.nlm.nih.gov/pubmed/26170232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv706
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