Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes

The design of heterologous prime-boost vaccine combinations that optimally shape the immune response is of critical importance for the development of next generation vaccines. Here, we tested different prime-boost combinations using the tuberculosis vaccine antigen H56 with CAF01 or CpG ODN 1826 adj...

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Vydáno v:Front Immunol
Hlavní autoři: Ciabattini, Annalisa, Prota, Gennaro, Christensen, Dennis, Andersen, Peter, Pozzi, Gianni, Medaglini, Donata
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551867/
https://ncbi.nlm.nih.gov/pubmed/26379666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00430
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