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Primary Activation of Antigen-Specific Naive CD4(+) and CD8(+) T Cells following Intranasal Vaccination with Recombinant Bacteria
The primary activation of T-helper and T-cytotoxic cells following mucosal immunization with recombinant Streptococcus gordonii was studied in vivo by adoptive transfer of ovalbumin (OVA)-specific transgenic CD8(+) (OT-I) and CD4(+) (OT-II) T cells. A recombinant strain, expressing on the surface th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2583588/ https://ncbi.nlm.nih.gov/pubmed/18838521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00793-08 |
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