Heterologous Prime-Boost Combinations Highlight the Crucial Role of Adjuvant in Priming the Immune System

The induction and modulation of the immune response to vaccination can be rationally designed by combining different vaccine formulations for priming and boosting. Here, we investigated the impact of heterologous prime-boost approaches on the vaccine-specific cellular and humoral responses specific...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ciabattini, Annalisa, Pettini, Elena, Fiorino, Fabio, Lucchesi, Simone, Pastore, Gabiria, Brunetti, Jlenia, Santoro, Francesco, Andersen, Peter, Bracci, Luisa, Pozzi, Gianni, Medaglini, Donata
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857569/
https://ncbi.nlm.nih.gov/pubmed/29593710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00380
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