Triterpenoid Saponin W3 from Anemone flaccida Suppresses Osteoclast Differentiation through Inhibiting Activation of MAPKs and NF-κB Pathways

Excessive bone resorption by osteoclasts within inflamed joints is the most specific hallmark of rheumatoid arthritis. A. flaccida has long been used for the treatment of arthritis in folk medicine of China; however, the active ingredients responsible for the anti-arthritis effects of A. flaccida ar...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Kong, Xiangying, Yang, Yue, Wu, Wenbin, Wan, Hongye, Li, Xiaomin, Zhong, Michun, Su, Xiaohui, Jia, Shiwei, Lin, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551756/
https://ncbi.nlm.nih.gov/pubmed/26327814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12296
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