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Triterpenoid Saponin W3 from Anemone flaccida Suppresses Osteoclast Differentiation through Inhibiting Activation of MAPKs and NF-κB Pathways

Excessive bone resorption by osteoclasts within inflamed joints is the most specific hallmark of rheumatoid arthritis. A. flaccida has long been used for the treatment of arthritis in folk medicine of China; however, the active ingredients responsible for the anti-arthritis effects of A. flaccida ar...

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Bibliografiska uppgifter
I publikationen:Int J Biol Sci
Huvudupphovsmän: Kong, Xiangying, Yang, Yue, Wu, Wenbin, Wan, Hongye, Li, Xiaomin, Zhong, Michun, Su, Xiaohui, Jia, Shiwei, Lin, Na
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551756/
https://ncbi.nlm.nih.gov/pubmed/26327814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12296
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