Triterpenoid Saponin W3 from Anemone flaccida Suppresses Osteoclast Differentiation through Inhibiting Activation of MAPKs and NF-κB Pathways

Excessive bone resorption by osteoclasts within inflamed joints is the most specific hallmark of rheumatoid arthritis. A. flaccida has long been used for the treatment of arthritis in folk medicine of China; however, the active ingredients responsible for the anti-arthritis effects of A. flaccida ar...

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Gepubliceerd in:Int J Biol Sci
Hoofdauteurs: Kong, Xiangying, Yang, Yue, Wu, Wenbin, Wan, Hongye, Li, Xiaomin, Zhong, Michun, Su, Xiaohui, Jia, Shiwei, Lin, Na
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2015
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551756/
https://ncbi.nlm.nih.gov/pubmed/26327814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.12296
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