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Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

Many regulatory agencies are exploring ways to integrate toxicogenomic data into their chemical risk assessments. The major challenge lies in determining how to distill the complex data produced by high-content, multi-dose gene expression studies into quantitative information. It has been proposed t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Webster, A. Francina, Chepelev, Nikolai, Gagné, Rémi, Kuo, Byron, Recio, Leslie, Williams, Andrew, Yauk, Carole L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551741/
https://ncbi.nlm.nih.gov/pubmed/26313361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136764
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