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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Genetic toxicology data have traditionally been employed for qualitative, rather than quantitative evaluations of hazard. As a continuation of our earlier report that analyzed ethyl methanesulfonate (EMS) and methyl methanesulfonate (MMS) dose–response data (Gollapudi et al., 2013), here we present...

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Τόπος έκδοσης:	Environ Mol Mutagen
Κύριοι συγγραφείς:	Johnson, G.E., Soeteman‐Hernández, L.G., Gollapudi, B.B., Bodger, O.G., Dearfield, K.L., Heflich, R.H., Hixon, J.G., Lovell, D.P., MacGregor, J.T., Pottenger, L.H., Thompson, C.M., Abraham, L., Thybaud, V., Tanir, J.Y., Zeiger, E., van Benthem, J., White, P.A.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	John Wiley and Sons Inc. 2014
Θέματα:	Research Articles
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6710644/ https://ncbi.nlm.nih.gov/pubmed/24801602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21870
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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

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