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Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer
BACKGROUND: Tapasin is a crucial component of the major histocompatibility (MHC) class I antigen presentation pathway. Defects in this pathway can lead to tumor immune evasion. The aim of this study was to test whether tapasin expression correlates with CD8(+) cytotoxic T lymphocyte (CTL) infiltrati...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551690/ https://ncbi.nlm.nih.gov/pubmed/26310568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0647-1 |
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