Molecular Genetics and Cellular Characteristics of TFE3 and TFEB Translocation Renal Cell Carcinomas

Despite nearly two decades since the discovery of gene fusions involving TFE3 or TFEB (“TFE”) in sporadic renal cell carcinoma (RCC), the molecular mechanisms underlying the renal-specific tumorigenesis remains largely unclear. The recent publication of the TCGA Network's clear cell kidney canc...

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Detalhes bibliográficos
Publicado no:Nat Rev Urol
Main Authors: Kauffman, Eric C., Ricketts, Christopher J., Rais-Bahrami, Soroush, Yang, Youfeng, Merino, Maria, Bottaro, Donald, Srinivasan, Ramaprasad, Linehan, W. Marston
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551450/
https://ncbi.nlm.nih.gov/pubmed/25048860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrurol.2014.162
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