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New Strategies in Renal Cell Carcinoma: Targeting the Genetic and Metabolic Basis of Disease

The development of new forms of treatment of advanced renal cell carcinoma over the past two decades has been primarily focused on targeting the VHL/HIF pathway. The recent identification of mutations of chromatin remodeling genes in clear cell renal carcinoma (RCC), of genomic heterogeneity and of...

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Detalles Bibliográficos
Publicado en:Clin Cancer Res
Main Authors: Srinivasan, Ramaprasad, Ricketts, Christopher J., Sourbier, Carole, Linehan, W. Marston
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795462/
https://ncbi.nlm.nih.gov/pubmed/25564569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2993
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