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Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a familial cancer syndrome associated with the development of cutaneous and uterine leiomyomas, and an aggressive form of type 2 papillary kidney cancer. HLRCC is characterized by germline mutation of the FH gene. This study evaluated the...

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Vocke, Cathy D., Ricketts, Christopher J., Merino, Maria J., Srinivasan, Ramaprasad, Metwalli, Adam R., Middelton, Lindsay A., Peterson, James, Yang, Youfeng, Linehan, W. Marston
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637959/
https://ncbi.nlm.nih.gov/pubmed/28196407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22452
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