Use of an anti-insulin receptor antibody to discriminate between metabolic and mitogenic effects of insulin: correlation with receptor autophosphorylation.

Ítems similars

• Insulin and rabbit anti-insulin receptor antibodies stimulate additively the intrinsic receptor kinase activity.
  per: Ponzio, G, et al.
  Publicat: (1987)
• Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation.
  per: Baron, V, et al.
  Publicat: (1989)
• Replacement of insulin receptor tyrosine residues 1162 and 1163 does not alter the mitogenic effect of the hormone.
  per: Debant, A, et al.
  Publicat: (1988)
• An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity.
  per: Herrera, R, et al.
  Publicat: (1985)
• Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts.
  per: Soos, M A, et al.
  Publicat: (1989)