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Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation.

Anti-peptide antibodies directed against a highly-conserved sequence of the insulin receptor tyrosine kinase domain have been used to study the relationship between this specific region and kinase activation. Antibodies have been prepared by the injection into a rabbit of a synthetic peptide (P2) co...

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Bibliografske podrobnosti
Main Authors: Baron, V, Gautier, N, Rochet, N, Ballotti, R, Rossi, B, Saint-Pierre, S, Van Obberghen, E, Dolais-Kitabgi, J
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138740/
https://ncbi.nlm.nih.gov/pubmed/2764902
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