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A Resveratrol Analogue Promotes ERK(MAPK)–Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells
(E)-4-(3,5-dimethoxystyryl)phenyl acetate (Cmpd1) is a resveratrol analog that preferentially inhibits glioma, breast, and pancreatic cancer cell growth, with IC(50) values of 6–19 μM. Notably, the human U251MG glioblastoma tumor line is the most sensitive, with an IC(50) of 6.7 μM, compared with no...
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| Publicado no: | Mol Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551051/ https://ncbi.nlm.nih.gov/pubmed/26138072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.099093 |
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