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Targeting STAT3 in cancer: how successful are we?
BACKGROUND: Aberrant activation of the signal transducer and activator of transcription (STAT)3 occurs in many human tumors. Moreover, studies utilizing genetic and pharmacological approaches to modulate constitutive STAT3 activity have provided compelling evidence for the critical role of aberrant...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610472/ https://ncbi.nlm.nih.gov/pubmed/19053881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543780802565791 |
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