A Perspective on Studying G-Protein–Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms

The last frontier for a complete understanding of G-protein–coupled receptor (GPCR) biology is to be able to assess GPCR activity, interactions, and signaling in vivo, in real time within biologically intact systems. This includes the ability to detect GPCR activity, trafficking, dimerization, prote...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Pharmacol
मुख्य लेखकों: van Unen, Jakobus, Woolard, Jeanette, Rinken, Ago, Hoffmann, Carsten, Hill, Stephen J., Goedhart, Joachim, Bruchas, Michael R., Bouvier, Michel, Adjobo-Hermans, Merel J. W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2015
विषय:
Minireview—Exploring the biology of GPCRs: from in vitro to in vivo
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551049/
https://ncbi.nlm.nih.gov/pubmed/25972446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.098897
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