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Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway

Endothelin signaling is essential for neural crest development, and dysregulated Endothelin signaling is associated with several neural crest-related disorders, including Waardenburg and other syndromes. However, despite the crucial roles of this pathway in neural crest development and disease, the...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Hu, Jianxin, Verzi, Michael P., Robinson, Ashley S., Tang, Paul Ling-Fung, Hua, Lisa L., Xu, Shan-Mei, Kwok, Pui-Yan, Black, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550968/
https://ncbi.nlm.nih.gov/pubmed/26160899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126391
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