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An arterial-specific enhancer of the human Endothelin-converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2

Endothelin-converting enzyme-1 (Ece-1), a crucial component of the Endothelin signaling pathway, is required for embryonic development and is an important regulator of vascular tone, yet the transcriptional regulation of the ECE1 gene has remained largely unknown. Here, we define the activity and re...

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Bibliografiske detaljer
Udgivet i:Dev Biol
Main Authors: Robinson, Ashley S., Materna, Stefan C., Barnes, Ralston M., De Val, Sarah, Xu, Shan-Mei, Black, Brian L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252918/
https://ncbi.nlm.nih.gov/pubmed/25179465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.08.027
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