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Endothelin converting enzyme (ECE) activity in human vascular smooth muscle

1. We have characterized the human smooth muscle endothelin converting enzyme (ECE) present in the media of the endothelium-denuded human umbilical vein preparation. 2. Endothelin-1 (ET-1) and ET-2 were potent constrictors of umbilical vein with EC(50) values of 9.2 nM and 29.6 nM, respectively. ET-...

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Библиографические подробности
Главные авторы: Maguire, Janet J, Johnson, Christopher M, Mockridge, James W, Davenport, Anthony P
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565120/
https://ncbi.nlm.nih.gov/pubmed/9422810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701564
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