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The transcription factor MEF2C is required for craniofacial development

MEF2 transcription factors are well-established regulators of muscle development. We have discovered an unanticipated role for MEF2C in the neural crest, where tissue-specific inactivation results in neonatal lethality due to severe craniofacial defects. We show that MEF2C is required for expression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Verzi, Michael P., Agarwal, Pooja, Brown, Courtney, McCulley, David J., Schwarz, John J., Black, Brian L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920108/
https://ncbi.nlm.nih.gov/pubmed/17420000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.03.007
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