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Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage

MEF2C is a member of the highly conserved MEF2 family of transcription factors and is a key regulator of cardiovascular development. In mice, Mef2c is expressed in the developing heart and vasculature, including the endothelium. Loss of Mef2c function in germline knockout mice leads to early embryon...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Materna, Stefan C., Sinha, Tanvi, Barnes, Ralston M., van Bueren, Kelly Lammerts, Black, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370303/
https://ncbi.nlm.nih.gov/pubmed/30521808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.12.002
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