Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

PURPOSE: We report the experience with 2,000 consecutive patients with advanced cancer who underwent testing on a genomic testing protocol, including the frequency of actionable alterations across tumor types, subsequent enrollment onto clinical trials, and the challenges for trial enrollment. PATIE...

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Опубликовано в: :J Clin Oncol
Главные авторы: Meric-Bernstam, Funda, Brusco, Lauren, Shaw, Kenna, Horombe, Chacha, Kopetz, Scott, Davies, Michael A., Routbort, Mark, Piha-Paul, Sarina A., Janku, Filip, Ueno, Naoto, Hong, David, De Groot, John, Ravi, Vinod, Li, Yisheng, Luthra, Raja, Patel, Keyur, Broaddus, Russell, Mendelsohn, John, Mills, Gordon B.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550690/
https://ncbi.nlm.nih.gov/pubmed/26014291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.60.4165
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