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Two pore channels control Ebolavirus host cell entry and are drug targets for disease treatment
Ebolavirus causes sporadic outbreaks of lethal hemorrhagic fever in humans with no currently approved therapy. Cells take up Ebolavirus by macropinocytosis, followed by trafficking through endosomal vesicles. However, few factors controlling endosomal virus movement are known. Here we find that Ebol...
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| Publicado en: | Science |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550587/ https://ncbi.nlm.nih.gov/pubmed/25722412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1258758 |
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