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Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function

Two-pore channels (TPCs) have recently emerged as a novel class of non-selective cation channels in the endolysosomal system. There are two members in the human genome, TPC1 and TPC2. Studies with TPC knockout and knockdown models have revealed that these channels participate in the regulation of mu...

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Pubblicato in:Front Pharmacol
Autori principali: Grimm, Christian, Chen, Cheng-Chang, Wahl-Schott, Christian, Biel, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293812/
https://ncbi.nlm.nih.gov/pubmed/28223936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00045
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