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Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function

Two-pore channels (TPCs) have recently emerged as a novel class of non-selective cation channels in the endolysosomal system. There are two members in the human genome, TPC1 and TPC2. Studies with TPC knockout and knockdown models have revealed that these channels participate in the regulation of mu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Grimm, Christian, Chen, Cheng-Chang, Wahl-Schott, Christian, Biel, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293812/
https://ncbi.nlm.nih.gov/pubmed/28223936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00045
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