Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients with Suspected Lynch Syndrome

BACKGROUND & AIMS: Multigene panels are commercially available tools for hereditary cancer risk assessment that allow for next-generation sequencing of numerous genes in parallel. However, it is not clear if these panels offer advantages over traditional genetic testing. We investigated the numb...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Yurgelun, Matthew B., Allen, Brian, Kaldate, Rajesh R., Bowles, Karla R., Judkins, Thaddeus, Kaushik, Praveen, Roa, Benjamin B., Wenstrup, Richard J., Hartman, Anne-Renee, Syngal, Sapna
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550537/
https://ncbi.nlm.nih.gov/pubmed/25980754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.006
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