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RECENTLY IDENTIFIED COLON CANCER PREDISPOSITIONS: MYH AND MSH6 MUTATIONS
Single-gene germline mutations conferring a high lifetime risk of CRC account for up to 6% of all CRC cases. The most widely studied monogenic colorectal cancer syndromes include Familial Adenomatous Polyposis (FAP) and Lynch syndrome. However, additional syndromes continue to be defined and new pre...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2259279/ https://ncbi.nlm.nih.gov/pubmed/17920897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2007.07.005 |
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