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Racial variations in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing

PURPOSE: To assess whether differences in frequency and phenotype of APC and MUTYH mutations exist among racially/ethnically diverse populations. METHODS: 6169 individuals with personal and/or family history of colorectal cancer (CRC) and polyps were studied. APC testing involved full sequencing/lar...

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Bibliographische Detailangaben
Veröffentlicht in:Genet Med
Hauptverfasser: Inra, Jennifer A., Steyerberg, Ewout W., Grover, Shilpa, McFarland, Ashley, Syngal, Sapna, Kastrinos, Fay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904772/
https://ncbi.nlm.nih.gov/pubmed/25590978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2014.199
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