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Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation

The cystic fibrosis transmembrane conductance regulator (CFTR) channel is activated by PKA phosphorylation of a regulatory domain that interacts dynamically with multiple CFTR domains and with other proteins. The large number of consensus sequences for phosphorylation by PKA has naturally focused mo...

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Bibliographic Details
Published in:FASEB J
Main Authors: Billet, Arnaud, Jia, Yanlin, Jensen, Tim, Riordan, John R., Hanrahan, John W.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550374/
https://ncbi.nlm.nih.gov/pubmed/26062600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-273151
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