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In silico design and analysis of a new hyperglycosylated analog of erythropoietin to improve drug efficacy

BACKGROUND: The enhancement of glycosylation by applying glycoengineering approaches has become widely used to boost properties for protein therapeutics. The objective of this work was to engineer a new hyperglycosylated analog of erythropoietin (EPO) with appropriately targeted N-linked carbohydrat...

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Detalhes bibliográficos
Publicado no:Adv Biomed Res
Main Authors: Kianmehr, Anvarsadat, Mohammadi, Hamid Shahbaz, Shokrgozar, Mohammad Ali, Omidinia, Eskandar
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549927/
https://ncbi.nlm.nih.gov/pubmed/26322290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.161548
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