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In silico design and analysis of a new hyperglycosylated analog of erythropoietin to improve drug efficacy
BACKGROUND: The enhancement of glycosylation by applying glycoengineering approaches has become widely used to boost properties for protein therapeutics. The objective of this work was to engineer a new hyperglycosylated analog of erythropoietin (EPO) with appropriately targeted N-linked carbohydrat...
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Publicado no: | Adv Biomed Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Medknow Publications & Media Pvt Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549927/ https://ncbi.nlm.nih.gov/pubmed/26322290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2277-9175.161548 |
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