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The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM

We have previously demonstrated that activation of the cyclic adenosine monophosphate (cAMP) pathway kills multiple myeloma (MM) cells both in vitro and in vivo. In the present study we have investigated the potential of enhancing the killing of MM cell lines and primary MM cells by combining the cA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Follin-Arbelet, Virginie, Misund, Kristine, Hallan Naderi, Elin, Ugland, Hege, Sundan, Anders, Kiil Blomhoff, Heidi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549684/
https://ncbi.nlm.nih.gov/pubmed/26306624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13001
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