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The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM

We have previously demonstrated that activation of the cyclic adenosine monophosphate (cAMP) pathway kills multiple myeloma (MM) cells both in vitro and in vivo. In the present study we have investigated the potential of enhancing the killing of MM cell lines and primary MM cells by combining the cA...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Follin-Arbelet, Virginie, Misund, Kristine, Hallan Naderi, Elin, Ugland, Hege, Sundan, Anders, Kiil Blomhoff, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549684/
https://ncbi.nlm.nih.gov/pubmed/26306624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13001
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