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Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor

Histone deacetylases (HDACs) act as corepressors in gene transcription by altering the acetylation of histones, resulting in epigenetic gene silencing. We previously reported that HDAC3 acts as a coactivator of the mineralocorticoid receptor (MR). Although HDAC3 forms complexes with class II HDACs,...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lee, Hae-Ahm, Song, Min-Ji, Seok, Young-Mi, Kang, Seol-Hee, Kim, Sang-Yeob, Kim, Inkyeom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549324/
https://ncbi.nlm.nih.gov/pubmed/26305553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136801
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