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Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats

Type 2 diabetes mellitus (T2DM) is a chronic disease manifested by hyperglycemia. It is essential to effectively control hyperglycemia to prevent complications of T2DM. Here, we hypothesize that repression of transcriptional activity of forkhead box O1 (FoxO1) via histone deacetylase inhibitors (HDA...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cho, Hyun Min, Seok, Young Mi, Lee, Hae Ahm, Song, Minji, Kim, InKyeom
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274985/
https://ncbi.nlm.nih.gov/pubmed/30424007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113539
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