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Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats

Type 2 diabetes mellitus (T2DM) is a chronic disease manifested by hyperglycemia. It is essential to effectively control hyperglycemia to prevent complications of T2DM. Here, we hypothesize that repression of transcriptional activity of forkhead box O1 (FoxO1) via histone deacetylase inhibitors (HDA...

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Pubblicato in:Int J Mol Sci
Autori principali: Cho, Hyun Min, Seok, Young Mi, Lee, Hae Ahm, Song, Minji, Kim, InKyeom
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274985/
https://ncbi.nlm.nih.gov/pubmed/30424007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113539
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