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Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism

OBJECTIVE: Aliskiren is a direct renin inhibitor which is suggested to modify proangiogenic cells in addition to lower blood pressure. Given that angiogenesis is impaired in the presence of diabetes mellitus, we would like to investigate whether and how aliskiren enhances endothelial progenitor cell...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chang, Ting-Ting, Wu, Tao-Cheng, Huang, Po-Hsun, Lin, Chih-Pei, Chen, Jia-Shiong, Lin, Liang-Yu, Lin, Shing-Jong, Chen, Jaw-Wen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549314/
https://ncbi.nlm.nih.gov/pubmed/26305217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136627
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