Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism

OBJECTIVE: Aliskiren is a direct renin inhibitor which is suggested to modify proangiogenic cells in addition to lower blood pressure. Given that angiogenesis is impaired in the presence of diabetes mellitus, we would like to investigate whether and how aliskiren enhances endothelial progenitor cell...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chang, Ting-Ting, Wu, Tao-Cheng, Huang, Po-Hsun, Lin, Chih-Pei, Chen, Jia-Shiong, Lin, Liang-Yu, Lin, Shing-Jong, Chen, Jaw-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549314/
https://ncbi.nlm.nih.gov/pubmed/26305217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136627
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