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Cyclooxygenase-2 and Prostaglandin E(2) Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection
Inflammation plays an important role in the pathophysiology of Chagas disease, caused by Trypanosoma cruzi. Prostanoids are regulators of homeostasis and inflammation and are produced mainly by myeloid cells, being cyclooxygenases, COX-1 and COX-2, the key enzymes in their biosynthesis from arachido...
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| Pubblicato in: | PLoS Negl Trop Dis |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549243/ https://ncbi.nlm.nih.gov/pubmed/26305786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004025 |
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