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Trypanosoma cruzi Infection and Endothelin-1 Cooperatively Activate Pathogenic Inflammatory Pathways in Cardiomyocytes

Trypanosoma cruzi, the causative agent of Chagas' disease, induces multiple responses in the heart, a critical organ of infection and pathology in the host. Among diverse factors, eicosanoids and the vasoactive peptide endothelin-1 (ET-1) have been implicated in the pathogenesis of chronic chag...

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Detalhes bibliográficos
Main Authors: Corral, Ricardo S., Guerrero, Néstor A., Cuervo, Henar, Gironès, Núria, Fresno, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566987/
https://ncbi.nlm.nih.gov/pubmed/23409199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002034
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