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Cyclooxygenase-2 and Prostaglandin E(2) Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection

Inflammation plays an important role in the pathophysiology of Chagas disease, caused by Trypanosoma cruzi. Prostanoids are regulators of homeostasis and inflammation and are produced mainly by myeloid cells, being cyclooxygenases, COX-1 and COX-2, the key enzymes in their biosynthesis from arachido...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Guerrero, Néstor A., Camacho, Mercedes, Vila, Luis, Íñiguez, Miguel A., Chillón-Marinas, Carlos, Cuervo, Henar, Poveda, Cristina, Fresno, Manuel, Gironès, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549243/
https://ncbi.nlm.nih.gov/pubmed/26305786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004025
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