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Identification of the Lomofungin Biosynthesis Gene Cluster and Associated Flavin-Dependent Monooxygenase Gene in Streptomyces lomondensis S015

Streptomyces lomondensis S015 synthesizes the broad-spectrum phenazine antibiotic lomofungin. Whole genome sequencing of this strain revealed a genomic locus consisting of 23 open reading frames that includes the core phenazine biosynthesis gene cluster lphzGFEDCB. lomo10, encoding a putative flavin...

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Publicat a:PLoS One
Autors principals: Zhang, Chunxiao, Sheng, Chaolan, Wang, Wei, Hu, Hongbo, Peng, Huasong, Zhang, Xuehong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549113/
https://ncbi.nlm.nih.gov/pubmed/26305803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136228
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