Investigations of the Flavin‐Dependent Monooxygenase PhzO Involved in Phenazine Biosynthesis

ABSTRACT Phenazines are bioactive secondary metabolites with antifungal, anticancer, and insecticidal properties, while hydroxylated derivatives often exhibit enhanced bioactivity. 2‐hydroxyphenazine (2‐OH‐PHZ), which is synthesised by the flavin‐dependent monooxygenase PhzO from phenazine‐1‐carboxy...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Yan‐Fang Nie, Sheng‐Jie Yue, Peng Huang, Xue‐Hong Zhang, Xiang‐Rui Hao, Lian Jiang, Hong‐Bo Hu
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2025-06-01
Serija:	Microbial Biotechnology
Teme:	3,4‐dihydroxy‐phenazine‐1‐carboxylic acid (3,4‐OH‐PCA) anticancer properties flavin reductase Fre monooxygenase PhzO phenazine biocatalysis promiscuous enzymatic activity
Online dostop:	https://doi.org/10.1111/1751-7915.70186
Oznake:	Označite Brez oznak, prvi označite!