Investigations of the Flavin‐Dependent Monooxygenase PhzO Involved in Phenazine Biosynthesis

ABSTRACT Phenazines are bioactive secondary metabolites with antifungal, anticancer, and insecticidal properties, while hydroxylated derivatives often exhibit enhanced bioactivity. 2‐hydroxyphenazine (2‐OH‐PHZ), which is synthesised by the flavin‐dependent monooxygenase PhzO from phenazine‐1‐carboxy...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yan‐Fang Nie, Sheng‐Jie Yue, Peng Huang, Xue‐Hong Zhang, Xiang‐Rui Hao, Lian Jiang, Hong‐Bo Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-06-01
coleção:	Microbial Biotechnology
Assuntos:	3,4‐dihydroxy‐phenazine‐1‐carboxylic acid (3,4‐OH‐PCA) anticancer properties flavin reductase Fre monooxygenase PhzO phenazine biocatalysis promiscuous enzymatic activity
Acesso em linha:	https://doi.org/10.1111/1751-7915.70186
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!